OneThree’s Workflow for Biomarker and Indication Selection

OneThree’s Workflow for Biomarker and Indication Selection Background OneThree Biotech was born out of the largest precision medicine institute in America with the purpose of decreasing the failure rate of bringing therapeutics to market using biology driven artificial intelligence. Our technology was built in a lab setting; allowing us to engineer our methodologies around real-world […]

Repositioning Approved Drugs as Combinations for MT Resistance

Repositioning Approved Drugs as Combinations for MT Resistance (This post relates to work done at Weill Cornell, where OneThree’s core technology was developed) This project is a bit of a followup from our previous collaboration with the Giannakakou lab where we identified and validated novel candidates that could act on cancer cells resistant to one […]

Predicting Genotype Specific Synergistic Combinations

Predicting Genotype Specific Synergistic Combinations (Before jumping in, I want to give a shout out to Coryandar Gilvary, a current graduate student at Weill Cornell. She led the work and was lead author on this method and is one of the best scientists working on machine learning for drug development I’ve met. This post relates […]